BDBM50363130 CHEMBL456911::Ro-28-2653

SMILES [O-][N+](=O)c1ccc(cc1)N1CCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NJKTYSXXGARILV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363130   

TargetMatrix metalloproteinase-9(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363130(Ro-28-2653 | CHEMBL456911)
Affinity DataIC50: 7nMAssay Description:Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363130(Ro-28-2653 | CHEMBL456911)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed