BDBM50363167 CHEMBL1945559

SMILES Cn1c2c(C(C#N)C3(CCNCC3)NC2=O)c2ccc(Cl)c(Cl)c12

InChI Key InChIKey=OWAWOKKHZNRHGV-UHFFFAOYSA-N

Data  3 KI  67 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 70 hits for monomerid = 50363167   

TargetSerine/threonine-protein kinase pim-1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 60nMAssay Description:Inhibition of PIM1 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 83nMAssay Description:Inhibition of CaMK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 90nMAssay Description:Inhibition of PIM3 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataKi:  140nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataKi:  140nMAssay Description:Inhibition of full length wild type CLK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 220nMAssay Description:Inhibition of ROCK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 240nMAssay Description:Inhibition of PIM2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 300nMAssay Description:Inhibition of PKN2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 310nMAssay Description:Inhibition of PKN1 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 330nMAssay Description:Inhibition of CK1alpha using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKCtheta using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MK5 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PKCalpha using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI4Kbeta using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PI3Kgamma using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PI3Kdelta using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of KDR using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of RET using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PI3Kbeta using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of mTOR using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of VPS34 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kalpha using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYN using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCK using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AXL using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Ins1R using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RON using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cMET using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4/D1 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cKIT using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSK using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COT1 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cABL using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER4 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAK using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphA4 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cSRC using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Ludwig-Maximilians University of Munich

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 70 total ) | Next | Last >>