BDBM50364652 CHEMBL1951350
SMILES CCn1c2c(ncnc2[nH]c1=O)-c1ccc(NC(=O)Nc2cccc(c2)C(=O)NC(C)C)cc1
InChI Key InChIKey=IVWHDODYYCRXLZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50364652
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 247nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human CYP3A4 in supersomes using midazolam as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair