BDBM50369495 CHEMBL606095

SMILES CC(C)NC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=FKRVKZRCTXANDS-LBXNUOQPSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50369495   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50369495(CHEMBL606095)
Affinity DataKi:  160nMAssay Description:Ability to displace radioligand [3H]- CGS 21680 from adenosine A2A receptor on rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50369495(CHEMBL606095)
Affinity DataKi:  211nMAssay Description:Ability to displace radioligand [125I]AB-MECA from membrane of HEK 293 cells stably transfected with human adenosine A3 receptor cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50369495(CHEMBL606095)
Affinity DataKi:  257nMAssay Description:Ability to displace radioligand [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane in the absence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50369495(CHEMBL606095)
Affinity DataKi:  804nMAssay Description:Ability to displace radioligand [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane in the presence of 1 mM of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50369495(CHEMBL606095)
Affinity DataEC50:  3.70E+4nMAssay Description:Effective concentration for cAMP production in CHO-KI cells stably transfected with human adenosine A2B receptor cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed