BDBM50375670 CHEMBL261425

SMILES O=C1Nc2ccccc2/C1=C\c1c(Cl)[nH]c2ccccc12

InChI Key InChIKey=QJKBRWSJWQVKLY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50375670   

TargetCyclin-dependent kinase 5 activator 1(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of GST-tagged CDK5/p25 (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate as substrate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of His-tagged CDK1/cyclin B1 (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of His-tagged CDK2/cyclin E (unknown origin) expressed in Baculovirus infected Sf9 cells using histone H1 as substrate in presence of [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Tartu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of GST-tagged CDK2/cyclin A2 (unknown origin) expressed in Escherichia coli using histone H1 as substrate in presence of [gamma-33P]-ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of GST-tagged AURORA B (unknown origin) expressed in baculovirus infected Sf9 cells using MBP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GST-tagged CDK7/cyclinH/MAT1 (unknown origin) expressed in Baculovirus infected Sf9 cells using YSPTSPS-2 KK peptide as substrate as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK4/cyclin D1 (unknown origin) expressed in Baculovirus infected Sf9 cells using RPPTLSPIPHIPR peptide as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged CDK9/CyclinT1 (unknown origin) expressed in Baculovirus infected Sf9 cells using YSPTSPS-2 KK peptide as substrate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Palack£

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged AURORA A (unknown origin) expressed in baculovirus infected Sf9 cells using MBP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375670BDBM50375670(CHEMBL261425)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Cdk5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed