BDBM50376007 CHEMBL406914

SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC(C)(C)C)c2cc1OC

InChI Key InChIKey=BVNOQDUIZJMQNL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50376007   

LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376007BDBM50376007(CHEMBL406914)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed