BDBM50388457 CHEMBL2059426

SMILES CC(NCC(C)(C)O)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1

InChI Key InChIKey=MRIYVMHCGWNLAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388457   

TargetMelanin-concentrating hormone receptor 1(RAT)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50388457(CHEMBL2059426)
Affinity DataIC50:  2.70nMAssay Description:Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50388457(CHEMBL2059426)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50388457(CHEMBL2059426)
Affinity DataIC50:  6.40nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-stimulated arachidonic acid release after 45 mins by liquid s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed