BDBM50392003 CHEMBL2152307

SMILES C(N1CCC(CC1)n1cnc2cnc3[nH]ccc3c12)c1cncnc1

InChI Key InChIKey=YNEDMIROJZALTC-UHFFFAOYSA-N

Data  1 KI  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392003   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL

LigandBDBM50392003(CHEMBL2152307)Copy SMILESCopy InChI

Affinity DataKi:  2nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL

LigandBDBM50392003(CHEMBL2152307)Copy SMILESCopy InChI

Affinity DataEC50:  350nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL2-induced STAT3 phosphorylationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL