BDBM50392684 CHEMBL2151353

SMILES OC1(CC(=O)c2ccc(cc2)-c2cccc(Cl)c2)C(=O)NC(=O)NC1=O

InChI Key InChIKey=HWKBTEUWFWNXHM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392684   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50392684(CHEMBL2151353)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition measured after 3 hrs by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50392684(CHEMBL2151353)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant MMP8 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50392684(CHEMBL2151353)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of recombinant MMP9 catalytic site using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg as substrate incubated for 30 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed