BDBM50392774 CHEMBL2151149

SMILES CCc1ccc2OC3(CCC3)C[C@H](NC[C@@H](O)[C@H](Cc3ccccc3)NC(C)=O)c2c1

InChI Key InChIKey=KSNAUJWJCQKJBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392774   

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392774(CHEMBL2151149)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392774(CHEMBL2151149)
Affinity DataIC50: 370nMAssay Description:Inhibition of BACE by cells based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50392774(CHEMBL2151149)
Affinity DataIC50: 700nMAssay Description:Inhibition of Cathepsin D (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed