BDBM50393228 CHEMBL2153750

SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2cc(F)ccc2n1

InChI Key InChIKey=UZCZCOMLMMSRLY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50393228   

TargetProtein kinase C beta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PKCbeta-1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PKCdelta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PKCeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PKCtheta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKCalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50393228(CHEMBL2153750)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKCepsilon by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed