BDBM50393842 CHEMBL2159749

SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12

InChI Key InChIKey=LDBQJXCAMFZXQH-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50393842   

TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition at human recombinant FAPalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  680nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  640nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  610nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  620nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  350nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  500nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  620nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  150nMAssay Description:Inhibition at human recombinant POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  580nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed