BDBM50394631 CHEMBL2164594::US9169224, 28

SMILES O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

InChI Key InChIKey=XVWZNBHOIBWEOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394631   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50:  80nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50:  74nMAssay Description:Inhibition of human FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50:  6.67E+3nMAssay Description:Inhibition of rat FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed