BDBM50397734 CHEMBL2181981

SMILES Brc1ccc(COC(=O)[C@H]2C[C@]3(CN2)C(=O)Nc2ccccc32)cc1

InChI Key InChIKey=OKOKOIXRZLVURN-VQIMIIECSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397734   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397734(CHEMBL2181981)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of human recombinant BACE1 using RGLTTRPGSGLTNIKTEEISEVNLDAEFRHDSGA as substrate after 1 hr by TMB-ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed