BDBM50418251 CHEMBL1614776
SMILES C[C@H]1CC[C@H](CN1c1cc(nc(N)n1)-c1ccc2c(N)[nH]nc2c1)NC(=O)OC(C)(C)C
InChI Key InChIKey=GAMJJHMLLXIWRZ-GXTWGEPZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50418251
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair