BDBM504210 N-(1-(3-Hydroxypropyl)-7- morpholino-2-oxo-1,2,3,4- tetrahydroquinolin-6- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 48

SMILES OCCCN1C(=O)CCc2cc(NC(=O)c3cnn4cccnc34)c(cc12)N1CCOCC1

InChI Key InChIKey=NYGFIZGVPAJVEP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504210   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504210(N-(1-(3-Hydroxypropyl)-7- morpholino-2-oxo-1,2,3,4...)
Affinity DataKi:  240nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent