BDBM504212 (R)—N-(3-(2-Cyanoethyl)-3-methyl-7-morpholinochroman-6-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US11034698, Example 58::US11034698, Example 59

SMILES C[C@@]1(CCC#N)COc2cc(N3CCOCC3)c(NC(=O)c3cnn4cccnc34)cc2C1

InChI Key InChIKey=KHMBYWWHAXGXIB-DEOSSOPVSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504212   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504212((R)—N-(3-(2-Cyanoethyl)-3-methyl-7-morpholino...)
Affinity DataKi:  19nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504212((R)—N-(3-(2-Cyanoethyl)-3-methyl-7-morpholino...)
Affinity DataKi:  30nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent