BDBM504275 US11034698, Example 154::US11034698, Example 155

SMILES CC1(C)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2[S@]1=O)N1CCOCC1

InChI Key InChIKey=FVGUNTUWWCOKJG-SSEXGKCCSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504275   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504275(US11034698, Example 154 | US11034698, Example 155)
Affinity DataKi:  22nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504275(US11034698, Example 154 | US11034698, Example 155)
Affinity DataKi:  560nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent