BDBM50434363 CHEMBL2386765::US9446044, 66
SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(F)cc4)c3c2s1
InChI Key InChIKey=KIMRTWGQATWAQF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50434363
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 6.06nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Dart Neuroscience
Curated by ChEMBL
Dart Neuroscience
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Dart Neuroscience
Curated by ChEMBL
Dart Neuroscience
Curated by ChEMBL
Affinity DataIC50: 9.64nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair