BDBM50434370 CHEMBL593252::GNF-Pf-3564::Thionin (14)

SMILES Nc1ccc2nc3ccc(=[NH2+])cc3sc2c1

InChI Key InChIKey=SHHZUHVSERGLNW-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434370   

TargetMicrotubule-associated protein tau(Human)
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434370(GNF-Pf-3564 | CHEMBL593252 | Thionin (14))
Affinity DataIC50: 69nMAssay Description:Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Human)
The Ohio State University

LigandPNGBDBM50434370(GNF-Pf-3564 | CHEMBL593252 | Thionin (14))
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMed