BDBM50434977 CHEMBL2385905
SMILES CCc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCc2c(C1)c1cccc(Cl)c1n2CC(O)=O
InChI Key InChIKey=UFMGJYNRGIGTIF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50434977
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]PGD2 from recombinant human prostanoid DP1 receptor expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2-induced calcium flux after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at human prostanoid TP2 receptor expressed in HEK293 cells assessed as inhibition of calcium flux after 30 to 40 mins by FLIPR as...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysis in...More data for this Ligand-Target Pair