BDBM50436695 CHEMBL2398642

SMILES OC1CCN(CCOc2ccc(cc2)-c2cc3c(NCCc4ccc(NC(=O)Nc5ccccc5)cc4)ncnc3o2)CC1

InChI Key InChIKey=WEVRAOPLGYJTLY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436695   

TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

LigandBDBM50436695(CHEMBL2398642)Copy SMILESCopy InChI

Affinity DataIC50:  41nMAssay Description:Inhibition of Aurora kinase A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetAurora kinase B(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

LigandBDBM50436695(CHEMBL2398642)Copy SMILESCopy InChI

Affinity DataIC50:  17nMAssay Description:Inhibition of Aurora kinase B (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI