BDBM50443616 CHEMBL3092413

SMILES Clc1ccc2nc(CN3CCN(CC3)c3ccc(cn3)C#N)cn2c1

InChI Key InChIKey=UGDJVSURAKMIPU-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50443616   

TargetG-protein coupled receptor 39(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443616(CHEMBL3092413)
Affinity DataEC50:  900nMAssay Description:Agonist activity at GPR39 in human HT-29 cells assessed as increase in intracellular Ca2+ mobilization after 72 hrs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 39(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443616(CHEMBL3092413)
Affinity DataEC50:  6.25E+3nMAssay Description:Agonist activity at human GPR39 receptor expressed in CHO cells assessed as increase in ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 39(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443616(CHEMBL3092413)
Affinity DataEC50:  56nMAssay Description:Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 39(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50443616(CHEMBL3092413)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed