BDBM50448641 CHEMBL3127518

SMILES c1cnccc1NC(=O)C2CC2

InChI Key InChIKey=GDEWBNVTMKLWQJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448641   

TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448641BDBM50448641(CHEMBL3127518)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of C-terminal His-tagged human full-length NAMPT expressed in Escherichia coli Rosetta DE3 using nicotinamide as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448641BDBM50448641(CHEMBL3127518)
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to NAMPT (2 to 491) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed