BDBM50448719 CHEMBL3124970

SMILES CCCSc1nc(C)sc1C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key InChIKey=CDUSNQGFNPWPJQ-CBJHUEPOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448719   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50448719(CHEMBL3124970)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50448719(CHEMBL3124970)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed