BDBM50449904 CHEMBL4174687

SMILES CCOc1cc(ccc1C1=NC(C(N1C(=O)NCCCCCCCC(=O)Nc1ccccc1N)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(C)(C)C

InChI Key InChIKey=HRHIMNJCOWFUGR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449904   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50449904(CHEMBL4174687)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of MDM2 (unknown origin) preincubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50449904(CHEMBL4174687)
Affinity DataIC50:  3.59E+3nMAssay Description:Inhibition of human recombinant full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed