BDBM50450399 CHEMBL4172116

SMILES CC(C)[C@@H](NC(=O)c1ccc(-c2ccc(CSc3nc4c(c(=O)[nH]3)CCC4)cc2)o1)C(=O)N[C@@H]1CCCC[C@H]1O

InChI Key InChIKey=QADIHDGYZDXXBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50450399   

TargetMatrix metalloproteinase-14(Human)
Graz University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450399BDBM50450399(CHEMBL4172116)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 expressed in Escherichia coli using fTHP-15 as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450399BDBM50450399(CHEMBL4172116)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450399BDBM50450399(CHEMBL4172116)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Graz University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450399BDBM50450399(CHEMBL4172116)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP9 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed