BDBM50454858 CHEMBL4218774

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O

InChI Key InChIKey=BNSADWSGWCWEGZ-UHFFFAOYSA-N

Data  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50454858   

TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454858BDBM50454858(CHEMBL4218774)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to biotinylated-KDM4A (unknown origin) at 300 nM by bio-layer interferometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454858BDBM50454858(CHEMBL4218774)
Affinity DataIC50: 34nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454858BDBM50454858(CHEMBL4218774)
Affinity DataIC50: 53nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454858BDBM50454858(CHEMBL4218774)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of full length FLAG-tagged KDM4A (unknown origin) expressed in human HeLa cells assessed as increase in H3K9me3 levels after 24 hrs by DAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed