BDBM50458048 CHEMBL4210944

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCc3n2)C(=O)C2CCN(C)CC2)ncc1F

InChI Key InChIKey=XPDLSCYMKCJIOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458048   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-E1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458048(CHEMBL4210944)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human CDK4/cyclin D1 using ULight-substrate after 1 hr by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458048(CHEMBL4210944)
Affinity DataIC50:  615nMAssay Description:Inhibition of human CDK1/Cyclin-B using ULight-substrate after 1 hr by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed