BDBM50459208 CHEMBL4214342

SMILES CN1C(=O)N(Cc2cnc(Nc3ccc(nc3)N3CCN(CC3)C(C)=O)nc12)c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=FCMNXGJPIJFWQV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459208   

TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Korea University

Curated by ChEMBL

LigandBDBM50459208(CHEMBL4214342)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of GCK (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

Target InfoMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL

LigandBDBM50459208(CHEMBL4214342)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of ACK1 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI