BDBM50468677 CHEMBL4282527

SMILES COc1ccc2c(c1)[nH]c(cc2=O)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=SULOYNMFUTYGFY-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50468677   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataKi:  45nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataKi:  376nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 5-lipoxygenase using arachidonic acid as substrate pretreated for 10 mins followed by substrate and ATP addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataIC50:  5.64E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate pretreated for 5 mins followed by substrate addition and measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50468677(CHEMBL4282527)
Affinity DataIC50:  7.27E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed