BDBM50472012 CHEMBL347076

SMILES CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccc(cc2)-c2ccccc2)C(O)=O)cc1)c1nc2ccccc2o1

InChI Key InChIKey=KARKKKSOIYWEQV-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50472012   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472012BDBM50472012(CHEMBL347076)
Affinity DataEC50:  24nMAssay Description:The compound was tested functionally in vitro for inducing 50% of the maximum alkaline phosphatase activity (Transactivation) against Peroxisome prol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472012BDBM50472012(CHEMBL347076)
Affinity DataKi:  49nMAssay Description:The compound was tested in vitro for inhibiting the 50% binding of Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472012BDBM50472012(CHEMBL347076)
Affinity DataEC50:  339nMAssay Description:-log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed