BDBM50476348 GSK-S-1360::GW-810781::Gw810781::S 1360::S-1360

SMILES O\C(=C/C(=O)c1ccc(Cc2ccc(F)cc2)o1)c1nc[nH]n1

InChI Key InChIKey=HFHDGHOGHWXXDT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50476348   

TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activity after 30 mins by polyacrylamide gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activity after 30 mins by polyacrylamide gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 600nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activity using [32P]5'end-labeled linear 21 mer as substrate incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase-mediated 3'-processing after 30 mins by polyacrylamide gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Universidade Federal Do Par£

Curated by ChEMBL
LigandPNGBDBM50476348(GSK-S-1360 | GW-810781 | Gw810781 | S 1360 | S-136...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase-mediated 3'-processing after 30 mins by polyacrylamide gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed