BDBM50476408 isotanshinone ii

SMILES Cc1coc-2c1C(=O)C(=O)c1ccc3c(C)cccc3c-21

InChI Key InChIKey=ONUSCCKLNWURMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476408   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50476408(isotanshinone ii)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Korean Research Institute of Biosciences and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50476408(isotanshinone ii)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed