BDBM50479983 Adefovir Diphosphate

SMILES Nc1ncnc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc12

InChI Key InChIKey=MELHEUHXJKQZNC-UHFFFAOYSA-N

Data  3 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50479983   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Afmb-Cnrs-Esil

Curated by ChEMBL
LigandPNGBDBM50479983(Adefovir Diphosphate)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to HIV1 wild type reverse transcriptase p66/p51 expressed in Escherichia coli assessed as incorporation of drug to DNA by gel electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM50479983(Adefovir Diphosphate)
Affinity DataIC50:  14nMAssay Description:Inhibition of Bacillus anthracis Edema factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM50479983(Adefovir Diphosphate)
Affinity DataIC50:  36nMAssay Description:Inhibition of Bacillus anthracis edema factor by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Afmb-Cnrs-Esil

Curated by ChEMBL
LigandPNGBDBM50479983(Adefovir Diphosphate)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase p66/p51 expressed in Escherichia coli using calf thymus DNA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed