BDBM504810 2-[2-Chloro-4-fluoro- 5-(7-morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-[1,2,4]- triazolo[4,3-a]pyridin- 5-ylacetamide::US11065253, Example 298

SMILES NC(=O)C(c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1)c1cncc2nncn12

InChI Key InChIKey=QMOHBWMSZVQDBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504810   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Merck Patent

US Patent
LigandPNGBDBM504810(US11065253, Example 298 | 2-[2-Chloro-4-fluoro- 5-...)
Affinity DataIC50: 18.5nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
US Patent