BDBM50487068 3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID

SMILES Cc1cc(C)cc(NC(P(O)(O)=O)P(O)(O)=O)c1

InChI Key InChIKey=CYEJULOSUMIQTQ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50487068   

TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataKi:  5.30E+4nMAssay Description:Non-competitive inhibition of Zea mays cv. Jeff( maize) leaf glutamine synthetase using L-glutamate as substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataKi:  5.50E+4nMAssay Description:Un-competitive inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using ATP as substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50:  1.07E+6nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50:  1.07E+6nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487068(3,5-DIMETHYLPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed