BDBM50494202 CHEMBL3086086

SMILES CNc1cc(ccn1)-c1cccnc1Oc1ccc(Nc2nc3ccc(F)c(F)c3[nH]2)cc1

InChI Key InChIKey=WUBLYECGKVDFTH-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494202   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50494202(CHEMBL3086086)Copy SMILESCopy InChI

Affinity DataIC50:  9.70nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FR...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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