BDBM50497442 CHEMBL3339301
SMILES COc1cc(\C=C\C(=O)OCCCCN(C)CCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC
InChI Key InChIKey=AIHHSLLQSRUQIA-ISLYRVAYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50497442
Affinity DataIC50: 63nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562/DOX cells at 3 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 2.00...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562 cells at 1 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 0.023 +/...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562/DOX cells at 1 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 2.00...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562 cells at 0.1 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 0.023 ...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562/DOX cells at 0.1 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 2....More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Modulatory activity at P-gp assessed as doxorubicin IC50 in human K562 cells at 3 uM after 72 hrs by MTT assay (Rvb doxorubicin alone IC50 = 0.023 +/...More data for this Ligand-Target Pair