BDBM505013 4-({4-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3- yl]benzyl} amino) benzonitrile::US11066396, Example 410

SMILES FC(F)(F)c1nc(no1)-c1ccc(CNc2ccc(cc2)C#N)cc1

InChI Key InChIKey=IHXHZYFDFGPIRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505013   

TargetHistone deacetylase 6(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM505013(4-({4-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3...)
Affinity DataIC50: 76nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
US Patent