BDBM50501843 CHEMBL4557232

SMILES COCc1nc(no1)-c1ccnc(n1)N1CCN(CC1)C(=O)c1ccc(\C=C2/Oc3c(cccc3C(N)=O)C2=O)cc1

InChI Key InChIKey=RXQSBZSFRJPXHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50501843   

TargetPoly [ADP-ribose] polymerase 2(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501843BDBM50501843(CHEMBL4557232)
Affinity DataIC50: 50nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501843BDBM50501843(CHEMBL4557232)
Affinity DataIC50: 50nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed