BDBM50501853 CHEMBL4475399

SMILES CC(C)(Cc1nc2ccccc2[nH]1)NC(=O)c1ccc(/C=C2\Oc3c(C(N)=O)cccc3C2=O)cc1

InChI Key InChIKey=MOUKRFDIPPHVSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50501853   

TargetPoly [ADP-ribose] polymerase 2(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501853BDBM50501853(CHEMBL4475399)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501853BDBM50501853(CHEMBL4475399)
Affinity DataIC50: 50nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed