BDBM50503336 CHEMBL4437377

SMILES O[C@@H]1CCN(C1)c1cc(ccc1CN1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PICHAYNTYNMQDD-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503336   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503336(CHEMBL4437377)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503336(CHEMBL4437377)
Affinity DataIC50:  2nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503336(CHEMBL4437377)
Affinity DataIC50:  8nMAssay Description:Inhibition of MGLL derived from mouse brain homogenates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM50503336(CHEMBL4437377)
Affinity DataIC50:  540nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed