BindingDB BDBM50505541 CHEMBL4465866

BDBM50505541 CHEMBL4465866

SMILES [H][C@]12C[C@@H](NCCOCCOCCOCCNC(=O)CCC3=[N+]4C(C=C3)=Cc3c(C)cc(C)n3[B-]4(F)F)[C@@H](OC)[C@](C)(O1)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13

InChI Key InChIKey=NXSJMRCTGYTSTK-UHFFFAOYSA-N

Data 200 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 200 hits for monomerid = 50505541

Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 1nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PHKG1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Mitogen-activated protein kinase kinase kinase 9(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 2nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP3K9 (unknown origin) (110 to 422 residues) expressed in baculovirus infected Sf9 in...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase kinase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 2nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMKK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Mitogen-activated protein kinase kinase kinase 11(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 3nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP3K11 (unknown origin) (99 to 398 residues) expressed in baculovirus infected Sf9 in...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase SIK1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 3nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-tagged SIK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incub...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Non-receptor tyrosine-protein kinase TNK1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 4nMAssay Description:Binding affinity to recombinant human N-terminal GST-tagged TNK1 (106 to 390 residues) expressed in baculovirus expression system using CSKtide as su...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit delta(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 4nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged CAMK2D expressed in baculovirus expression system using GS peptide as substra...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Ribosomal protein S6 kinase alpha-3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 4nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged RPS6KA3 expressed in baculovirus expression system using S6K peptide as subst...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase SIK2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 4nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SIK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase pim-3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 4nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PIM3 expressed in baculovirus expression system using S6K2 peptide as substra...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal his-tagged PDK1 expressed in baculovirus infected Sf9 insect cells incubated for 1 hr by...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase PAK 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 5nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PAK4 expressed in baculovirus expression system using SGKtide as substrate in...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

STE20-like serine/threonine-protein kinase(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 5nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged SLK (unknown origin) (1 to 1152 residues) expressed in baculovirus infected Sf9 insect...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase MARK2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MARK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

AP2-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged AAK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

MAP/microtubule affinity-regulating kinase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MARK4 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase N2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PKN2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Mitogen-activated protein kinase kinase kinase kinase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MAP4K2 (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

LIM domain kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 6nMAssay Description:Binding affinity to truncated human N-terminal GST-tagged LIMK1 (285 to 638 residues) expressed in baculovirus expression system using cofilin2 as su...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 7nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK4 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase MRCK gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 7nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DMPK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase 33(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 8nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged STK33 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

3-phosphoinositide-dependent protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 8nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PDPK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Non-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 8nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged TYK2 (unknown origin) (871 to 1187 residues) expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 8nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMK2G (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Ribosomal protein S6 kinase alpha-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 8nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged RPS6KA2 expressed in baculovirus expression system using S6K peptide as subst...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase MARK1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 9nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-tagged MARK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

NUAK family SNF1-like kinase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 10nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-tagged NUAK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incu...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase SIK3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 10nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged SIK3 (unknown origin) (59 to 365 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase N1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 11nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PKN1 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 11nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CAMKK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

MAP/microtubule affinity-regulating kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 13nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged MARK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Protein kinase C delta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 13nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged PRKCD expressed in baculovirus expression system using PKC peptide as substra...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 13nMAssay Description:Binding affinity to recombinant human full-length GST N-Terminal tagged-AMPK alpha1/N-Terminal GST tagged-AMPK beta1/N-Terminal his-tagged AMPK gamma...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Tyrosine-protein kinase JAK3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 14nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged JAK3 (unknown origin) (795 to 1124 residues) expressed in baculovirus infe...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Tyrosine-protein kinase JAK2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 14nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged JAK2 (unknown origin) (826 to 1132 residues) expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase pim-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 15nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PIM2 expressed in baculovirus expression system using S6K2 peptide as substra...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit alpha(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 15nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged CAMK2A expressed in baculovirus expression system using GS peptide as substra...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

NUAK family SNF1-like kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 15nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged NUAK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase ULK3(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 16nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged ULK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Ribosomal protein S6 kinase alpha-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 16nMAssay Description:Binding affinity to recombinant full length human N-terminal GST-tagged RPS6KA1 expressed in baculovirus expression system using S6K peptide as subst...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase TBK1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 17nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged TBK1 expressed in baculovirus expression system using CKtide as substrate inc...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Mitogen-activated protein kinase kinase kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 17nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged MAP4K1 (unknown origin) (1 to 346 residues) expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Testis-specific serine/threonine-protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 18nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TSSK1B (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 19nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged CAMK2B expressed in baculovirus expression system using GS peptide as substra...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase Chk1(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 20nMAssay Description:Binding affinity to recombinant human full-length N-terminal His-tagged CHEK1 expressed in baculovirus expression system using CHKtide as substrate i...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Ribosomal protein S6 kinase alpha-6(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 21nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-tagged RPS6KA6 (unknown origin) expressed in baculovirus infected Sf9 insect cells in...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

Serine/threonine-protein kinase PAK 6(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 22nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged PAK6 expressed in baculovirus expression system using SGKtide as substrate in...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

NT-3 growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL

BDBM50505541(CHEMBL4465866)

Kd: 23nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged NTRK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Date in BDB:
2/18/2021
Entry Details Article
PubMed

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Filter my 200 hits

Targets 200▿
- Tyrosine-protein kinase Tec 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 1
- BMP-2-inducible protein kinase 1
- Rhodopsin kinase GRK1 1
- LIM domain kinase 1 1
- ALK tyrosine kinase receptor 1
- NUAK family SNF1-like kinase 2 1
- Non-receptor tyrosine-protein kinase TYK2 1
- Glycogen synthase kinase-3 beta 1
- Protein kinase C iota type 1
- NUAK family SNF1-like kinase 1 1
- AP2-associated protein kinase 1 1
- Calcium/calmodulin-dependent protein kinase type II subunit beta 1
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1
- Protein kinase C theta type 1
- Serine/threonine-protein kinase PAK 4 1
- Serine/threonine-protein kinase PAK 5 1
- Serine/threonine-protein kinase PAK 6 1
- Tyrosine-protein kinase JAK3 1
- Tyrosine-protein kinase JAK2 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Dual specificity mitogen-activated protein kinase kinase 6 1
- Dual specificity mitogen-activated protein kinase kinase 7 1
- Tyrosine-protein kinase ZAP-70 1
- Serine/threonine-protein kinase Sgk2 1
- Serine/threonine-protein kinase Sgk1 1
- Serine/threonine-protein kinase Sgk3 1
- Myosin light chain kinase 3 1
- Ephrin type-A receptor 1 1
- Ephrin type-A receptor 3 1
- Tyrosine-protein kinase BTK 1
- Ephrin type-A receptor 4 1
- Ephrin type-A receptor 7 1
- Tyrosine-protein kinase receptor UFO 1
- Cyclin-C 1
- Cyclin-A2/Cyclin-dependent kinase 2 1
- Tyrosine-protein kinase Lyn 1
- Focal adhesion kinase 1 1
- Tyrosine-protein kinase TXK 1
- Ephrin type-A receptor 8 1
- Death-associated protein kinase 2 1
- Death-associated protein kinase 1 1
- Serine/threonine-protein kinase D2 1
- TGF-beta receptor type-2 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1
- Death-associated protein kinase 3 1
- Serine/threonine-protein kinase pim-3 1
- Serine/threonine-protein kinase pim-1 1
- Serine/threonine-protein kinase pim-2 1
- Testis-specific serine/threonine-protein kinase 1 1
- Protein kinase C epsilon type 1
- Testis-specific serine/threonine-protein kinase 3 1
- Leukocyte tyrosine kinase receptor 1
- Cytoplasmic tyrosine-protein kinase BMX 1
- Tyrosine-protein kinase ABL2 1
- Tyrosine-protein kinase ABL1 1
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 1
- cGMP-dependent protein kinase 2 1
- Rho-associated protein kinase 2 1
- cGMP-dependent protein kinase 1 1
- Rho-associated protein kinase 1 1
- Serine/threonine-protein kinase ULK1 1
- Serine/threonine-protein kinase SIK2 1
- Tyrosine-protein kinase Fes/Fps 1
- Serine/threonine-protein kinase SIK1 1
- Serine/threonine-protein kinase SIK3 1
- Serine/threonine-protein kinase ULK2 1
- Serine/threonine-protein kinase ULK3 1
- 3-phosphoinositide-dependent protein kinase 1 1
- Serine/threonine-protein kinase 3 1
- Serine/threonine-protein kinase 4 1
- Mitogen-activated protein kinase 8 1
- Tyrosine-protein kinase SYK 1
- Serine/threonine-protein kinase TBK1 1
- Serine/threonine-protein kinase 32B 1
- Serine/threonine-protein kinase 32A 1
- Serine/threonine-protein kinase 32C 1
- Vascular endothelial growth factor receptor 2 1
- Insulin receptor 1
- Tyrosine-protein kinase HCK 1
- Vascular endothelial growth factor receptor 3 1
- Serine/threonine-protein kinase PLK4 1
- Tyrosine-protein kinase receptor TYRO3 1
- Serine/threonine-protein kinase BRSK1 1
- Serine/threonine-protein kinase LATS2 1
- Protein kinase C gamma type 1
- cAMP-dependent protein kinase catalytic subunit alpha 1
- Citron Rho-interacting kinase 1
- Protein kinase C zeta type 1
- Serine/threonine-protein kinase Chk2 1
- Serine/threonine-protein kinase Chk1 1
- cAMP-dependent protein kinase catalytic subunit PRKX 1
- Tyrosine-protein kinase Yes 1
- Serine/threonine-protein kinase MRCK gamma 1
- Peripheral plasma membrane protein CASK 1
- Receptor tyrosine-protein kinase erbB-4 1
- Tyrosine-protein kinase FRK 1
- Hepatocyte growth factor receptor 1
- Glycogen synthase kinase-3 alpha 1
- MAP/microtubule affinity-regulating kinase 3 1
- Homeodomain-interacting protein kinase 4 1
- Homeodomain-interacting protein kinase 3 1
- MAP kinase-interacting serine/threonine-protein kinase 2 1
- MAP/microtubule affinity-regulating kinase 4 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- Serine/threonine-protein kinase 38-like 1
- Myosin-IIIb 1
- Tyrosine-protein kinase ITK/TSK 1
- Myotonin-protein kinase 1
- Protein kinase C eta type 1
- Tyrosine-protein kinase Blk 1
- Serine/threonine-protein kinase 16 1
- Non-receptor tyrosine-protein kinase TNK1 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Ribosomal protein S6 kinase beta-1 1
- Protein kinase C beta type 1
- Serine/threonine-protein kinase 26 1
- Serine/threonine-protein kinase 24 1
- Serine/threonine-protein kinase 25 1
- Serine/threonine-protein kinase 33 1
- Ephrin type-B receptor 4 1
- cAMP-dependent protein kinase catalytic subunit gamma 1
- Ephrin type-B receptor 2 1
- Activated CDC42 kinase 1 1
- Ephrin type-B receptor 6 1
- Platelet-derived growth factor receptor beta 1
- Epithelial discoidin domain-containing receptor 1 1
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1
- Tyrosine-protein kinase Fer 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 1
- Calcium/calmodulin-dependent protein kinase type II subunit delta 1
- Proto-oncogene tyrosine-protein kinase ROS 1
- Serine/threonine-protein kinase TAO1 1
- Calcium/calmodulin-dependent protein kinase kinase 1 1
- Serine/threonine-protein kinase TAO3 1
- Calcium/calmodulin-dependent protein kinase kinase 2 1
- Serine/threonine-protein kinase DCLK3 1
- Serine/threonine-protein kinase TNNI3K 1
- Angiopoietin-1 receptor 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Mitogen-activated protein kinase kinase kinase kinase 1 1
- Serine/threonine-protein kinase MRCK alpha 1
- Mitogen-activated protein kinase kinase kinase kinase 5 1
- Mitogen-activated protein kinase 15 1
- Cyclin-dependent kinase 5 activator 1 1
- Interleukin-1 receptor-associated kinase 4 1
- Mitogen-activated protein kinase kinase kinase 9 1
- RAC-gamma serine/threonine-protein kinase 1
- Mitogen-activated protein kinase kinase kinase 5 1
- Interleukin-1 receptor-associated kinase 1 1
- Mitogen-activated protein kinase kinase kinase 7 1
- Mitogen-activated protein kinase kinase kinase 2 1
- Cyclin-C/Cyclin-dependent kinase 19 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Myosin light chain kinase, smooth muscle 1
- Serine/threonine-protein kinase 17A 1
- Tyrosine-protein kinase Lck 1
- Dual specificity protein kinase CLK1 1
- CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 1
- Mitogen-activated protein kinase kinase kinase 14 1
- Protein kinase C delta type 1
- NT-3 growth factor receptor 1
- Dual specificity protein kinase CLK4 1
- Dual specificity protein kinase CLK2 1
- High affinity nerve growth factor receptor 1
- Protein-tyrosine kinase 2-beta 1
- Tyrosine-protein kinase Mer 1
- Serine/threonine-protein kinase N2 1
- cAMP-dependent protein kinase catalytic subunit beta 1
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 1
- Serine/threonine-protein kinase N1 1
- Ribosomal protein S6 kinase alpha-2 1
- Ribosomal protein S6 kinase alpha-3 1
- Ribosomal protein S6 kinase alpha-1 1
- Cyclin-T1/Cyclin-dependent kinase 9 1
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 1
- STE20-like serine/threonine-protein kinase 1
- Calcium/calmodulin-dependent protein kinase type 1G 1
- Fibroblast growth factor receptor 4 1
- Tyrosine-protein kinase Fgr 1
- Aurora kinase A 1
- Fibroblast growth factor receptor 1 1
- Fibroblast growth factor receptor 2 1
- Fibroblast growth factor receptor 3 1
- Mitogen-activated protein kinase 12 1
- RAC-beta serine/threonine-protein kinase 1
- Mitogen-activated protein kinase 10 1
- Misshapen-like kinase 1 1
- Tyrosine-protein kinase Fyn 1
- Tyrosine-protein kinase CSK 1
- Macrophage colony-stimulating factor 1 receptor 1
- Ribosomal protein S6 kinase alpha-6 1
- Protein kinase C alpha type 1
- Maternal embryonic leucine zipper kinase 1
- Ribosomal protein S6 kinase alpha-5 1
- Serine/threonine-protein kinase MARK1 1
- Serine/threonine-protein kinase MARK2 1
- TRAF2 and NCK-interacting protein kinase 1
- Mitogen-activated protein kinase kinase kinase 11 1
Publications 1▿
- Bioorg Med Chem Lett 29: (2019) 200
Institutions 1▿
- Takeda Pharmaceutical 200
Affinity: 1 to 1.9E+3 nM▿
- Kd 200
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0