BDBM50506054 CHEMBL4440185

SMILES CC(C)OC(=O)[C@H](C)N(C(=O)c1ccco1)c1c(Cl)cccc1Cl

InChI Key InChIKey=QVXCXYZAVANRBK-NSHDSACASA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506054   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50506054(CHEMBL4440185)
Affinity DataIC50:  29nMAssay Description:Displacement of RIP140 cofactor peptide from human His6-tagged RORgammat LBD (264 to 518 residues) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50506054(CHEMBL4440185)
Affinity DataIC50:  452nMAssay Description:Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB