BDBM50507406 CHEMBL4452218

SMILES OC(=O)CNC(=O)c1c(O)c2cccc3NC(Cn(c23)c1=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=VSGUVLRZXLNZOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507406   

TargetEgl nine homolog 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507406(CHEMBL4452218)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507406(CHEMBL4452218)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507406(CHEMBL4452218)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed