BDBM50508011 CHEMBL4455302

SMILES COc1cc2ncnc(C3CCN(CC3)C(=O)c3ccc(C)cc3)c2cc1OC

InChI Key InChIKey=UICPBWJEYSWKSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508011   

TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50508011(CHEMBL4455302)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50508011(CHEMBL4455302)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed