BDBM50509411 CHEMBL4552089
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]3n1cnc2c1nc[nH]c2=O
InChI Key InChIKey=KHPSNOLQNDOWJF-XPWFQUROSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50509411
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 2.99E+4nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataKd: 64nMAssay Description:Binding affinity to wild-type human STING-CTD (139-379) expressed in Escherichia coli BL21(D Escherichia ) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 1.25E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 5.43E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 1.55E+4nMAssay Description:Activation of STING in human blood assessed as induction of type I IFNs incubated for 18 to 20 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute Of Organic Chemistry And Biochemistry Of The Czech Academy Of Sciences And Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ...More data for this Ligand-Target Pair