BDBM50515646 CHEMBL4583833

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(NCc2ccc(Br)cc2)cc1

InChI Key InChIKey=CMKXDEWFJXQZDF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515646   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515646BDBM50515646(CHEMBL4583833)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed