BDBM50517659 CHEMBL4439095
SMILES CC(C)Oc1ncccc1CNc1ncc(C#N)c(NCC23CC4CC(C2)C(NC[C@H]2CC[C@H](O)CC2)C(C4)C3)n1
InChI Key InChIKey=WXLDNPCGXLYSOG-RJQVWWFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50517659
Affinity DataIC50: 18nMAssay Description:Inhibition of PKCtheta in human Jurkat cells assessed as reduction in IL2 production after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant human full length PKCtheta using biotin-labelled STK substrate-1 as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair