BDBM50517659 CHEMBL4439095

SMILES CC(C)Oc1ncccc1CNc1ncc(C#N)c(NCC23CC4CC(C2)C(NC[C@H]2CC[C@H](O)CC2)C(C4)C3)n1

InChI Key InChIKey=WXLDNPCGXLYSOG-RJQVWWFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517659   

TargetProtein kinase C theta type(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50517659(CHEMBL4439095)
Affinity DataIC50:  18nMAssay Description:Inhibition of PKCtheta in human Jurkat cells assessed as reduction in IL2 production after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50517659(CHEMBL4439095)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of recombinant human full length PKCtheta using biotin-labelled STK substrate-1 as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed